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TitleAffinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1.
Journal, issue, pagesMabs, Vol. 7, Page 152-, Year 2015
Publish dateAug 4, 2014 (structure data deposition date)
AuthorsDouthwaite, J.A. / Sridharan, S. / Huntington, C. / Hammersley, J. / Marwood, R. / Hakulinen, J.K. / Ek, M. / Sjogren, T. / Rider, D. / Privezentzev, C. ...Douthwaite, J.A. / Sridharan, S. / Huntington, C. / Hammersley, J. / Marwood, R. / Hakulinen, J.K. / Ek, M. / Sjogren, T. / Rider, D. / Privezentzev, C. / Seaman, J.C. / Cariuk, P. / Knights, V. / Young, J. / Wilkinson, T. / Sleeman, M. / Finch, D.K. / Lowe, D.C. / Vaughan, T.J.
External linksMabs / PubMed:25484051
MethodsX-ray diffraction
Resolution3.08 Å
Structure data

PDB-4uv4:
Crystal structure of anti-FPR Fpro0165 Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 3.08 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / ANTIBODY ENGINEERING / PHAGE DISPLAY / LONG CDR / FORMYL PEPTIDE RECEPTOR-1

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