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Structure paper

TitleActivation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
Journal, issue, pagesStructure, Vol. 22, Page 1786-1798, Year 2014
Publish dateNov 16, 2012 (structure data deposition date)
AuthorsJilkova, A. / Horn, M. / Rezacova, P. / Maresova, L. / Fajtova, P. / Brynda, J. / Vondrasek, J. / McKerrow, J.H. / Caffrey, C.R. / Mares, M.
External linksStructure / PubMed:25456815
MethodsX-ray diffraction
Resolution1.3 - 1.95 Å
Structure data

PDB-4i04:
Structure of zymogen of cathepsin B1 from Schistosoma mansoni
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4i05:
Structure of intermediate processing form of cathepsin B1 from Schistosoma mansoni
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4i07:
Structure of mature form of cathepsin B1 from Schistosoma mansoni
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

Source
  • schistosoma mansoni (invertebrata)
KeywordsHYDROLASE / peptidase / digestive tract

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