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Structure paper

TitleHuman ficolin-2 recognition versatility extended: An update on the binding of ficolin-2 to sulfated/phosphated carbohydrates.
Journal, issue, pagesFebs Lett., Vol. 588, Page 4694-4700, Year 2014
Publish dateSep 5, 2014 (structure data deposition date)
AuthorsLaffly, E. / Lacroix, M. / Martin, L. / Vassal-Stermann, E. / Thielens, N.M. / Gaboriaud, C.
External linksFebs Lett. / PubMed:25447524
MethodsX-ray diffraction
Resolution2.1 - 2.25 Å
Structure data

PDB-4r9j:
L-ficolin complexed to glucosamine-6-sulfate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4r9t:
L-ficolin complexed to sulphates
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-3LJ:
2-amino-2-deoxy-6-O-sulfo-alpha-D-glucopyranose

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / FIBRINOGEN-LIKE domain / INNATE IMMUNITY / PATTERN RECOGNITION PROTEIN / LECTIN / IMMUNOLOGY / LECTIN-LIKE / plasma / extracellular

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