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-Structure paper
Title | Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 10, Page 591-600, Year 2015 |
Publish date | Oct 8, 2014 (structure data deposition date) |
![]() | Lahiri, S.D. / Mangani, S. / Jahic, H. / Benvenuti, M. / Durand-Reville, T.F. / De Luca, F. / Ehmann, D.E. / Rossolini, G.M. / Alm, R.A. / Docquier, J.D. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 2.4 Å |
Structure data | ![]() PDB-4wm9: ![]() PDB-4wmc: |
Chemicals | ![]() ChemComp-NXL: ![]() ChemComp-SO4: ![]() ChemComp-EDO: ![]() ChemComp-CO2: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / beta-lactamase / class D carbapenemase / inhibitor / OXA-48 / Avibactam |