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Structure paper

TitleThe First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 682-690, Year 2015
Publish dateApr 3, 2014 (structure data deposition date)
AuthorsMarx, A. / Alian, A.
External linksJ. Biol. Chem. / PubMed:25404739
MethodsX-ray diffraction
Resolution2.6 - 2.9 Å
Structure data

PDB-4p9c:
Crystal structure of dCMP deaminase from the cyanophage S-TIM5 in complex with dCMP and dUMP
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4p9d:
Crystal structure of dCMP deaminase from the cyanophage S-TIM5 in complex with dTMP and dTTP.
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-4p9e:
Crystal structure of dCMP deaminase from the cyanophage S-TIM5 in apo form
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-DCM:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE

ChemComp-DU:
2'-DEOXYURIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-CL:
Unknown entry

Source
  • cyanophage s-tim5 (virus)
KeywordsHYDROLASE / dCMP deaminase / cytidine deaminase / deoxycytidylate deaminase / S-TIM5 / S-TIM5 cyanophage

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