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-Structure paper
Title | Discovery of 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one Derivatives as a New Series of Potent Phosphodiesterase 7 Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 9844-9854, Year 2014 |
Publish date | May 20, 2014 (structure data deposition date) |
Authors | Kawai, K. / Endo, Y. / Asano, T. / Amano, S. / Sawada, K. / Ueo, N. / Takahashi, N. / Sonoda, Y. / Nagai, M. / Kamei, N. / Nagata, N. |
External links | J. Med. Chem. / PubMed:25383422 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-4pm0: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-32V: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / phosphodiesterase / PDE7 |