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Structure paper

TitleStructural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.
Journal, issue, pagesPlos Pathog., Vol. 10, Page e1004377-e1004377, Year 2014
Publish dateFeb 13, 2014 (structure data deposition date)
AuthorsSpindler, N. / Diestel, U. / Stump, J.D. / Wiegers, A.K. / Winkler, T.H. / Sticht, H. / Mach, M. / Muller, Y.A.
External linksPlos Pathog. / PubMed:25299639
MethodsX-ray diffraction
Resolution1.87 - 2.11 Å
Structure data

PDB-4osu:
Crystal structure of HCMV gB-neutralizing SM5-1 Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4ot1:
Structural Basis for the Recognition of Human Cytomegalovirus Glycoprotein B by the Neutralizing Human Antibody SM5-1
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

Source
  • homo sapiens (human)
  • human cytomegalovirus
KeywordsIMMUNE SYSTEM / Immunoglobulin / Immune response / HCMV neutralization / HCMV glycoprotein B / VIRAL PROTEIN/IMMUNE SYSTEM / PH domain / Antibody-Antigen Recognition / VIRAL PROTEIN-IMMUNE SYSTEM complex

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