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Structure paper

TitleHuman Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 70, Page 2765-, Year 2014
Publish dateMay 28, 2014 (structure data deposition date)
AuthorsZakova, L. / Klevtikova, E. / Lepsik, M. / Collinsova, M. / Watson, C.J. / Turkenburg, J.P. / Jiracek, J. / Brzozowski, A.M.
External linksActa Crystallogr. ,Sect. D / PubMed:25286859
MethodsX-ray diffraction
Resolution1.59 - 2.75 Å
Structure data

PDB-4une:
Human insulin B26Phe mutant crystal structure
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

PDB-4ung:
Human insulin B26Asn mutant crystal structure
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-4unh:
Human insulin B26Gly mutant crystal structure
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE / B26 SITE

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