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Title | Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 8268-8279, Year 2014 |
Publish date | Dec 15, 2013 (structure data deposition date) |
Authors | Snasel, J. / Naus, P. / Dostal, J. / Hnizda, A. / Fanfrlik, J. / Brynda, J. / Bourderioux, A. / Dusek, M. / Dvorakova, H. / Stolarikova, J. ...Snasel, J. / Naus, P. / Dostal, J. / Hnizda, A. / Fanfrlik, J. / Brynda, J. / Bourderioux, A. / Dusek, M. / Dvorakova, H. / Stolarikova, J. / Zabranska, H. / Pohl, R. / Konecny, P. / Dzubak, P. / Votruba, I. / Hajduch, M. / Rezacova, P. / Veverka, V. / Hocek, M. / Pichova, I. |
External links | J. Med. Chem. / PubMed:25259627 |
Methods | X-ray diffraction |
Resolution | 1.5 - 2.5 Å |
Structure data | PDB-4o1g: PDB-4o1l: PDB-4pvv: |
Chemicals | ChemComp-NA: ChemComp-AGS: ChemComp-HOH: ChemComp-MG: ChemComp-HO4: |
Source |
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Keywords | TRANSFERASE / Adenosine Kinase / Transferase/Transferase inhibitor / Transferase-Transferase inhibitor complex |