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Structure paper

TitleGlobal Profiling of Co- and Post-Translationally N-Myristoylated Proteomes in Human Cells.
Journal, issue, pagesNat. Commun., Vol. 5, Page 4919-, Year 2014
Publish dateAug 20, 2013 (structure data deposition date)
AuthorsThinon, E. / Serwa, R.A. / Broncel, M. / Brannigan, J.A. / Brassat, U. / Wright, M.H. / Heal, W.P. / Wilkinson, A.J. / Mann, D.J. / Tate, E.W.
External linksNat. Commun. / PubMed:25255805
MethodsX-ray diffraction
Resolution1.64 - 2.33 Å
Structure data

PDB-4c2x:
Human N-myristoyltransferase isoform 2 (NMT2)
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

PDB-4c2y:
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA co-factor
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

PDB-4c2z:
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and inhibitor bound
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NHW:
2-oxopentadecyl-CoA

ChemComp-HOH:
WATER

ChemComp-MYA:
TETRADECANOYL-COA

ChemComp-CIT:
CITRIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-646:
2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / MYRISTOYLATION

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