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-Structure paper
Title | Structures of a pan-specific antagonist antibody complexed to different isoforms of TGF beta reveal structural plasticity of antibody-antigen interactions. |
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Journal, issue, pages | Protein Sci., Vol. 23, Page 1698-1707, Year 2014 |
Publish date | May 22, 2013 (structure data deposition date) |
![]() | Moulin, A. / Mathieu, M. / Lawrence, C. / Bigelow, R. / Levine, M. / Hamel, C. / Marquette, J.P. / Le Parc, J. / Loux, C. / Ferrari, P. ...Moulin, A. / Mathieu, M. / Lawrence, C. / Bigelow, R. / Levine, M. / Hamel, C. / Marquette, J.P. / Le Parc, J. / Loux, C. / Ferrari, P. / Capdevila, C. / Dumas, J. / Dumas, B. / Rak, A. / Bird, J. / Qiu, H. / Pan, C.Q. / Edmunds, T. / Wei, R.R. |
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Methods | X-ray diffraction |
Resolution | 2.83 - 3 Å |
Structure data | ![]() PDB-4kv5: ![]() PDB-4kxz: |
Chemicals | ![]() ChemComp-MES: ![]() ChemComp-PE5: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / Cysteine knot / Fab / TGF-beta receptor mimetic / TGF-beta / TGF-beta receptor / Various growth functions (TGF-beta) / TGF-beta antagonist (GC2008) / TGF-beta receptors |