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-Structure paper
Title | Structure-Activity Relationship of 3,5-Diaryl-2-Aminopyridine Alk2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 7900-, Year 2014 |
Publish date | Mar 26, 2013 (structure data deposition date) |
![]() | Mohedas, A.H. / Wang, Y. / Sanvitale, C.E. / Canning, P. / Choi, S. / Xing, X. / Bullock, A.N. / Cuny, G.D. / Yu, P.B. |
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Methods | X-ray diffraction |
Resolution | 2.56 Å |
Structure data | ![]() PDB-4bgg: |
Chemicals | ![]() ChemComp-844: ![]() ChemComp-FLC: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / INHIBITOR / BMP SIGNALLING |