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TitleCompensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
Journal, issue, pagesJ. Immunol., Vol. 193, Page 2135-2146, Year 2014
Publish dateFeb 28, 2014 (structure data deposition date)
AuthorsLamont, D. / Mukherjee, G. / Kumar, P.R. / Samanta, D. / McPhee, C.G. / Kay, T.W.H. / Almo, S.C. / DiLorenzo, T.P. / Serreze, D.V.
External linksJ. Immunol. / PubMed:25063871
MethodsX-ray diffraction
Resolution1.98 - 2.335 Å
Structure data

PDB-3ws3:
Crystal Structure of H-2D in complex with an insulin derived peptide
Method: X-RAY DIFFRACTION / Resolution: 2.335 Å

PDB-3ws6:
Crystal Structure of H-2D in complex with a mimotopic peptide
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-IMD:
IMIDAZOLE

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Class I MHC / Major histocompatibility complex / insulin / H-2D / Structural Genomics / PSI-Biology / New York Structural Genomics Research Consortium / NYSGRC / mimotope

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