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TitlePhosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page E3177-, Year 2014
Publish dateNov 30, 2012 (structure data deposition date)
AuthorsGoni, G.M. / Epifano, C. / Boskovic, J. / Camacho-Artacho, M. / Zhou, J. / Bronowska, A. / Martin, M.T. / Eck, M.J. / Kremer, L. / Grater, F. ...Goni, G.M. / Epifano, C. / Boskovic, J. / Camacho-Artacho, M. / Zhou, J. / Bronowska, A. / Martin, M.T. / Eck, M.J. / Kremer, L. / Grater, F. / Gervasio, F.L. / Perez-Moreno, M. / Lietha, D.
External linksProc. Natl. Acad. Sci. USA / PubMed:25049397
MethodsX-ray diffraction
Resolution3.15 - 3.2 Å
Structure data

PDB-3zdt:
Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-4cye:
Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsTRANSFERASE / CELL ADHESION / FAK / FERM DOMAIN

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