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Structure paper

TitleCrystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 10526-, Year 2014
Publish dateJun 13, 2014 (structure data deposition date)
AuthorsSchweizer, U. / Schlicker, C. / Braun, D. / Kohrle, J. / Steegborn, C.
External linksProc. Natl. Acad. Sci. USA / PubMed:25002520
MethodsX-ray diffraction
Resolution1.9 - 1.93 Å
Structure data

PDB-4tr3:
Mouse iodothyronine deiodinase 3 catalytic core, SeMet-labeled active site mutant SeCys->Cys
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4tr4:
Mouse iodothyronine deiodinase 3 catalytic core, active site mutant SeCys->Cys
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / deiodinase / thyronine hormones / thioredoxin fold

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