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Structure paper

TitleStructural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 24549-24559, Year 2014
Publish dateApr 15, 2014 (structure data deposition date)
AuthorsBasu, R.S. / Warner, B.A. / Molodtsov, V. / Pupov, D. / Esyunina, D. / Fernandez-Tornero, C. / Kulbachinskiy, A. / Murakami, K.S.
External linksJ. Biol. Chem. / PubMed:24973216
MethodsX-ray diffraction
Resolution2.9 - 3 Å
Structure data

PDB-4q4z:
Thermus thermophilus RNA polymerase de novo transcription initiation complex
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-4q5s:
Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-2TM:
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine

ChemComp-HOH:
WATER

Source
  • thermus thermophilus (bacteria)
  • thermus thermophilus hb8 (bacteria)
Keywordstranscription/DNA / transcription / DNA and NTP / transcription-DNA complex / transcription/DNA/rna / transcription-DNA-rna complex

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