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Structure paper

TitleInteractions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Journal, issue, pagesAcs Chem. Biol., Vol. 9, Page 1712-1717, Year 2014
Publish dateJan 13, 2014 (structure data deposition date)
AuthorsLi, Y.C. / Ho, I.H. / Ku, C.C. / Zhong, Y.Q. / Hu, Y.P. / Chen, Z.G. / Chen, C.Y. / Lin, W.C. / Zulueta, M.M. / Hung, S.C. ...Li, Y.C. / Ho, I.H. / Ku, C.C. / Zhong, Y.Q. / Hu, Y.P. / Chen, Z.G. / Chen, C.Y. / Lin, W.C. / Zulueta, M.M. / Hung, S.C. / Lin, M.G. / Wang, C.C. / Hsiao, C.D.
External linksAcs Chem. Biol. / PubMed:24959968
MethodsX-ray diffraction
Resolution1.5 - 1.8 Å
Structure data

PDB-4oee:
Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4oef:
Crystal Structure Analysis of FGF2-Disaccharide (S6I2) complex
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4oeg:
Crystal Structure Analysis of FGF2-Disaccharide (S9I2) complex
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Heparin/Heparin Sulfate Binding

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