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-Structure paper
Title | Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 5, Page 700-705, Year 2014 |
Publish date | Feb 21, 2014 (structure data deposition date) |
![]() | Hu, E. / Andrews, K. / Chmait, S. / Zhao, X. / Davis, C. / Miller, S. / Hill Della Puppa, G. / Dovlatyan, M. / Chen, H. / Lester-Zeiner, D. ...Hu, E. / Andrews, K. / Chmait, S. / Zhao, X. / Davis, C. / Miller, S. / Hill Della Puppa, G. / Dovlatyan, M. / Chen, H. / Lester-Zeiner, D. / Able, J. / Biorn, C. / Ma, J. / Shi, J. / Treanor, J. / Allen, J.R. |
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Methods | X-ray diffraction |
Resolution | 2.08 - 2.243 Å |
Structure data | ![]() PDB-4p0n: ![]() PDB-4p1r: |
Chemicals | ![]() ChemComp-1IS: ![]() ChemComp-1IR: ![]() ChemComp-ZN: ![]() ChemComp-SO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-2KR: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / HYDROLASE/HYDROLASE INBHITOR / HYDROLASE-HYDROLASE INBHITOR complex |