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Structure paper

TitleFolate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 449, Page 392-398, Year 2014
Publish dateApr 4, 2014 (structure data deposition date)
AuthorsLuka, Z. / Pakhomova, S. / Loukachevitch, L.V. / Newcomer, M.E. / Wagner, C.
External linksBiochem. Biophys. Res. Commun. / PubMed:24858690
MethodsX-ray diffraction
Resolution1.85 - 2.32 Å
Structure data

PDB-4p9s:
Crystal structure of the mature form of rat DMGDH
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

PDB-4paa:
Crystal structure of the mature form of rat DMGDH complexed with tetrahydrofolate
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

PDB-4pab:
Crystal structure of the precursor form of rat DMGDH complexed with tetrahydrofolate
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

ChemComp-THG:
(6S)-5,6,7,8-TETRAHYDROFOLATE

ChemComp-SCN:
THIOCYANATE ION

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / dimethylglycine dehydrogenase / rat / tetrahydrofolate

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