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TitleVarp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Journal, issue, pagesDev. Cell, Vol. 29, Page 591-, Year 2014
Publish dateApr 13, 2014 (structure data deposition date)
AuthorsHesketh, G.G. / Perez-Dorado, I. / Jackson, L.P. / Wartosch, L. / Schefer, I.B. / Gray, S.R. / Mccoy, A.J. / Zeldin, O.B. / Garman, E.F. / Harbour, M.E. ...Hesketh, G.G. / Perez-Dorado, I. / Jackson, L.P. / Wartosch, L. / Schefer, I.B. / Gray, S.R. / Mccoy, A.J. / Zeldin, O.B. / Garman, E.F. / Harbour, M.E. / Evans, P.R. / Seaman, M.N. / Luzio, J.P. / Owen, D.J.
External linksDev. Cell / PubMed:24856514
MethodsX-ray diffraction
Resolution2.8 - 2.97 Å
Structure data

PDB-4cym:
Complex of human VARP-ANKRD1 with Rab32-GppCp
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-4cz2:
Complex of human VARP-ANKRD1 with Rab32-GppCp. Selenomet derivative.
Method: X-RAY DIFFRACTION / Resolution: 2.97 Å

Chemicals

ChemComp-GCP:
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER / GMP-PCP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / VARP / RAB-EFFECTOR / RAB / ENDOSOME / VESICLE TRAFFICKING / MELANOSOME BIOGENESIS / SIGNALING PROTEIN

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