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TitleStructure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved alpha-helix for Act1 binding and IL-17 signaling.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 70, Page 1476-1483, Year 2014
Publish dateDec 4, 2013 (structure data deposition date)
AuthorsZhang, B. / Liu, C. / Qian, W. / Han, Y. / Li, X. / Deng, J.
External linksActa Crystallogr. ,Sect. D / PubMed:24816115
MethodsX-ray diffraction
Resolution2.295 Å
Structure data

PDB-4nux:
Structure of receptor A
Method: X-RAY DIFFRACTION / Resolution: 2.295 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / SEFIR domain / cytokine / receptor / autoimmune inflammatory

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