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Structure paper

TitleStructural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Journal, issue, pagesMol. Cell, Vol. 54, Page 879-886, Year 2014
Publish dateMar 18, 2014 (structure data deposition date)
AuthorsZhou, T. / Xiong, J. / Wang, M. / Yang, N. / Wong, J. / Zhu, B. / Xu, R.M.
External linksMol. Cell / PubMed:24813944
MethodsX-ray diffraction
Resolution2.001 - 3.789 Å
Structure data

PDB-4pw5:
structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I
Method: X-RAY DIFFRACTION / Resolution: 2.204 Å

PDB-4pw6:
structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II
Method: X-RAY DIFFRACTION / Resolution: 3.789 Å

PDB-4pw7:
structure of UHRF2-SRA in complex with a 5mC-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE/DNA / SRA / 5hmC binding / 5hmC-containing DNA / hydroxymethylation / nuclear / LIGASE-DNA complex / methylation

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