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Structure paper

TitleEffect of CDR3 Sequences and Distal V Gene Residues in Regulating TCR-MHC Contacts and Ligand Specificity.
Journal, issue, pagesJ Immunol., Vol. 192, Page 6071-6082, Year 2014
Publish dateFeb 28, 2014 (structure data deposition date)
AuthorsStadinski, B.D. / Trenh, P. / Duke, B. / Huseby, P.G. / Li, G. / Stern, L.J. / Huseby, E.S.
External linksJ Immunol. / PubMed:24813203
MethodsX-ray diffraction
Resolution2.25 - 3.263 Å
Structure data

PDB-4p23:
J809.B5 TCR bound to IAb/3K
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4p46:
J809.B5 Y31A TCR bound to IAb3K
Method: X-RAY DIFFRACTION / Resolution: 2.851 Å

PDB-4p5t:
14.C6 TCR complexed with MHC class II I-Ab/3K peptide
Method: X-RAY DIFFRACTION / Resolution: 3.263 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TCR MHC peptide / TCR MHCII / MHC / TCR / immune receptor / Ig-like domain

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