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TitleChloride Sensing by WNK1 Involves Inhibition of Autophosphorylation.
Journal, issue, pagesSci. Signal., Vol. 7, Page ra41-ra41, Year 2014
Publish dateMar 20, 2014 (structure data deposition date)
AuthorsPiala, A.T. / Moon, T.M. / Akella, R. / He, H. / Cobb, M.H. / Goldsmith, E.J.
External linksSci. Signal. / PubMed:24803536
MethodsX-ray diffraction
Resolution1.84 - 3.5 Å
Structure data

PDB-4pwn:
Crystal structure of Active WNK1 kinase
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-4q2a:
WNK1: A chloride sensor via autophosphorylation
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / kinase / WNK1 / Ser/Thr protein kinase / Serine/Threonine kinase / ATP-binding / phosphorylation / protein serine/threonine kinase / unphosphorylated

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