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Structure paper

TitleStructural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Journal, issue, pagesGenes Dev., Vol. 28, Page 929-, Year 2014
Publish dateApr 9, 2014 (structure data deposition date)
AuthorsDias, J. / Van Nguyen, N. / Georgiev, P. / Gaub, A. / Brettschneider, J. / Cusack, S. / Kadlec, J. / Akhtar, A.
External linksGenes Dev. / PubMed:24788516
MethodsX-ray diffraction
Resolution1.4 - 2.3 Å
Structure data

PDB-4cy1:
Crystal structure of the KANSL1-WDR5 complex.
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4cy2:
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4cy3:
Crystal structure of the NSL1-WDS complex.
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-4cy5:
Crystal structure of the NSL1-WDS-NSL2 complex.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • drosophila melanogaster (fruit fly)
KeywordsTRANSCRIPTION / EPIGENETIC REGULATOR / HISTONE ACETYLATION / CHROMATIN

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