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Structure paper

TitleStructural insights into regulatory mechanisms of MO25-mediated kinase activation.
Journal, issue, pagesJ. Struct. Biol., Vol. 186, Page 224-233, Year 2014
Publish dateDec 13, 2013 (structure data deposition date)
AuthorsHao, Q. / Feng, M. / Shi, Z. / Li, C. / Chen, M. / Wang, W. / Zhang, M. / Jiao, S. / Zhou, Z.
External linksJ. Struct. Biol. / PubMed:24746913
MethodsX-ray diffraction
Resolution3.185 - 3.583 Å
Structure data

PDB-4nzw:
Crystal Structure of STK25-MO25 Complex
Method: X-RAY DIFFRACTION / Resolution: 3.583 Å

PDB-4o27:
Crystal structure of MST3-MO25 complex with WIF motif
Method: X-RAY DIFFRACTION / Resolution: 3.185 Å

Chemicals

ChemComp-J60:
5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE ACTIVATOR/TRANSFERASE / scafolding protein / Ser/Thr protein kinase / TRANSFERASE ACTIVATOR-TRANSFERASE complex / Scaffold protein / Protein Ser/Thr kinase / SIGNALING PROTEIN

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