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Structure paper

TitleReceptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Journal, issue, pagesNat Commun, Vol. 5, Page 3614-3614, Year 2014
Publish dateDec 19, 2013 (structure data deposition date)
AuthorsLee, P.S. / Ohshima, N. / Stanfield, R.L. / Yu, W. / Iba, Y. / Okuno, Y. / Kurosawa, Y. / Wilson, I.A.
External linksNat Commun / PubMed:24717798
MethodsX-ray diffraction
Resolution1.5045 - 6.501 Å
Structure data

PDB-4o58:
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
Method: X-RAY DIFFRACTION / Resolution: 2.7501 Å

PDB-4o5i:
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
Method: X-RAY DIFFRACTION / Resolution: 6.501 Å

PDB-4o5l:
Crystal structure of broadly neutralizing antibody F045-092
Method: X-RAY DIFFRACTION / Resolution: 1.5045 Å

PDB-4o5n:
Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

Source
  • influenza a virus
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / immunoglobulin / virus attachment and entry / immune recognition / VIRAL PROTEIN-IMMUNE SYSTEM complex / IMMUNE SYSTEM / Fab / Fragment antigen binding / Immunoglobulin fold / VIRAL PROTEIN / viral fusion protein

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