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| Title | Crystal Structure of Eml1 Reveals the Basis for Hsp90 Dependence of Oncogenic Eml4-Alk by Disruption of an Atypical Beta-Propeller Domain. |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 111, Page 5195-, Year 2014 |
| Publish date | Dec 6, 2013 (structure data deposition date) |
Authors | Richards, M.W. / Law, E.W.P. / Rennalls, L.P. / Busacca, S. / O'Regan, L. / Fry, A.M. / Fennell, D.A. / Bayliss, R. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:24706829 |
| Methods | X-ray diffraction |
| Resolution | 2.6 Å |
| Structure data | ![]() PDB-4ci8: |
| Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
| Source |
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Keywords | STRUCTURAL PROTEIN / EML1 / EML4-ALK / HSP90 INHIBITORS / TUBULIN-BINDING / BETA PROPELLER |
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homo sapiens (human)
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