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TitleMetabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae.
Journal, issue, pagesPlos One, Vol. 9, Page e92662-e92662, Year 2014
Publish dateAug 28, 2012 (structure data deposition date)
AuthorsMitchell, S.N. / Rigden, D.J. / Dowd, A.J. / Lu, F. / Wilding, C.S. / Weetman, D. / Dadzie, S. / Jenkins, A.M. / Regna, K. / Boko, P. ...Mitchell, S.N. / Rigden, D.J. / Dowd, A.J. / Lu, F. / Wilding, C.S. / Weetman, D. / Dadzie, S. / Jenkins, A.M. / Regna, K. / Boko, P. / Djogbenou, L. / Muskavitch, M.A. / Ranson, H. / Paine, M.J. / Mayans, O. / Donnelly, M.J.
External linksPlos One / PubMed:24675797
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4gsn:
Crystal Structure of GSTe2 ZAN/U variant from Anopheles gambiae
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GSH:
GLUTATHIONE

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • anopheles gambiae (African malaria mosquito)
KeywordsTRANSFERASE / GST

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