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TitleRole of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 70, Page 708-, Year 2014
Publish dateJan 28, 2013 (structure data deposition date)
AuthorsPonomarenko, N.A. / Chatziefthimiou, S.D. / Kurkova, I.N. / Mokrushina, Y.A. / Stepanova, A.V. / Smirnov, I.V. / Avakyan, E.M. / Bobik, T.V. / Mamedov, A. / Mitkevich, V.A. ...Ponomarenko, N.A. / Chatziefthimiou, S.D. / Kurkova, I.N. / Mokrushina, Y.A. / Stepanova, A.V. / Smirnov, I.V. / Avakyan, E.M. / Bobik, T.V. / Mamedov, A. / Mitkevich, V.A. / Belogurov, A.J. / Fedorova, O.S. / Dubina, M. / Golovin, A. / Lamzin, V.S. / Friboulet, A. / Makarov, A.A. / Wilmanns, M. / Gabibov, A.G.
External linksActa Crystallogr. ,Sect. D / PubMed:24598740
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-3zl4:
Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM

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