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TitleA Novel Ige-Neutralizing Antibody for the Treatment of Severe Uncontrolled Asthma.
Journal, issue, pagesMabs, Vol. 6, Page 756-, Year 2015
Publish dateSep 7, 2015 (structure data deposition date)
AuthorsCohen, E.S. / Dobson, C.L. / Kack, H. / Wang, B. / Sims, D.A. / Lloyd, C.O. / England, E. / Rees, D.G. / Guo, H. / Karagiannis, S.N. ...Cohen, E.S. / Dobson, C.L. / Kack, H. / Wang, B. / Sims, D.A. / Lloyd, C.O. / England, E. / Rees, D.G. / Guo, H. / Karagiannis, S.N. / O'Brien, S. / Persdotter, S. / Ekdahl, H. / Butler, R. / Keyes, F. / Oakley, S. / Carlsson, M. / Briend, E. / Wilkinson, T. / Anderson, I.K. / Monk, P.D. / Von Wachenfeldt, K. / Eriksson, P.F. / Gould, H.J. / Vaughan, T.J. / May, R.D.
External linksMabs / PubMed:24583620
MethodsX-ray diffraction
Resolution2.85 Å
Structure data

PDB-5anm:
Crystal structure of IgE Fc in complex with a neutralizing antibody
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / THERAPEUTIC ANTIBODY / IGG / IGE / ASTHMA

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