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TitleIdentification of a new hormone-binding site on the surface of thyroid hormone receptor.
Journal, issue, pagesMol. Endocrinol., Vol. 28, Page 534-545, Year 2014
Publish dateJul 12, 2013 (structure data deposition date)
AuthorsSouza, P.C. / Puhl, A.C. / Martinez, L. / Aparicio, R. / Nascimento, A.S. / Figueira, A.C. / Nguyen, P. / Webb, P. / Skaf, M.S. / Polikarpov, I.
External linksMol. Endocrinol. / PubMed:24552590
MethodsX-ray diffraction
Resolution1.9 - 2.05 Å
Structure data

PDB-4lnw:
Crystal structure of TR-alpha bound to T3 in a second site
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4lnx:
Crystal structure of TR-alpha bound to T4 in a second site
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-T3:
3,5,3'TRIIODOTHYRONINE / hormone*YM

ChemComp-HOH:
WATER

ChemComp-T44:
3,5,3',5'-TETRAIODO-L-THYRONINE / hormone*YM

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Mainly Alpha Orthogonal Bundle / Transcription factor

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