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Structure paper

TitleStructure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.
Journal, issue, pagesNucleic Acids Res., Vol. 42, Page 4741-4754, Year 2014
Publish dateNov 8, 2013 (structure data deposition date)
AuthorsAik, W. / Scotti, J.S. / Choi, H. / Gong, L. / Demetriades, M. / Schofield, C.J. / McDonough, M.A.
External linksNucleic Acids Res. / PubMed:24489119
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-4nj4:
Crystal Structure of Human ALKBH5
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-NO3:
NITRATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-UN9:
N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOxidoreductase/Oxidoreductase inhibitor / double-stranded beta helix / jelly-roll motif / dioxygenase / RNA demethylase / RNA / Oxidoreductase-Oxidoreductase inhibitor complex

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