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TitleStructure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Journal, issue, pagesNat Commun, Vol. 5, Page 3067-3067, Year 2014
Publish dateNov 10, 2013 (structure data deposition date)
AuthorsLu, L. / Liu, Q. / Zhu, Y. / Chan, K.H. / Qin, L. / Li, Y. / Wang, Q. / Chan, J.F. / Du, L. / Yu, F. ...Lu, L. / Liu, Q. / Zhu, Y. / Chan, K.H. / Qin, L. / Li, Y. / Wang, Q. / Chan, J.F. / Du, L. / Yu, F. / Ma, C. / Ye, S. / Yuen, K.Y. / Zhang, R. / Jiang, S.
External linksNat Commun / PubMed:24473083
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4njl:
Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

Source
  • middle east respiratory syndrome coronavirus
KeywordsVIRAL PROTEIN / six-helix-bundle / coronavirus / MERS-Cov / fusion inhibitor / fusion core

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