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Structure paper

TitleStructural evidence for a constrained conformation of short CDR-L3 in antibodies.
Journal, issue, pagesProteins, Vol. 82, Page 1679-1683, Year 2014
Publish dateMay 14, 2013 (structure data deposition date)
AuthorsTeplyakov, A. / Obmolova, G. / Malia, T.J. / Luo, J. / Gilliland, G.L.
External linksProteins / PubMed:24470236
MethodsX-ray diffraction
Resolution1.92 - 2.7 Å
Structure data

PDB-4kq3:
Crystal structure of Anti-IL-17A antibody CNTO3186
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-4kuz:
Crystal structure of anti-emmprin antibody 4A5 Fab in trigonal form
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / immunoglobulin fold

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