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Structure paper

TitleThe crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Journal, issue, pagesNucleic Acids Res., Vol. 42, Page 4712-4722, Year 2014
Publish dateJan 21, 2013 (structure data deposition date)
AuthorsKuo, P.H. / Chiang, C.H. / Wang, Y.T. / Doudeva, L.G. / Yuan, H.S.
External linksNucleic Acids Res. / PubMed:24464995
MethodsX-ray diffraction
Resolution2.752 Å
Structure data

PDB-4iuf:
Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA
Method: X-RAY DIFFRACTION / Resolution: 2.752 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION REGULATOR/DNA / RNA Recognition Motif / RNA binding / DNA binding / splicing factor / TRANSCRIPTION REGULATOR-DNA complex / PROTEIN-DNA COMPLEX

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