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Structure paper

TitleRed Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Journal, issue, pagesPlos Pathog., Vol. 10, Page e1003869-e1003869, Year 2014
Publish dateDec 4, 2013 (structure data deposition date)
AuthorsBatchelor, J.D. / Malpede, B.M. / Omattage, N.S. / Dekoster, G.T. / Henzler-Wildman, K.A. / Tolia, N.H.
External linksPlos Pathog. / PubMed:24415938
MethodsX-ray diffraction
Resolution1.95 - 2.6 Å
Structure data

PDB-4nuu:
Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4nuv:
Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • plasmodium vivax (malaria parasite P. vivax)
  • homo sapiens (human)
Keywordsmembrane protein / cell invasion / Duffy Binding Like (DBL) Domain Fold / GPCR / Adhesion / Invasion / Red blood cell binding / Chemokine Binding / Duffy Antigen Receptor for Chemokines / Membrane / protein binding

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