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Structure paper

TitleStructural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Journal, issue, pagesNat Commun, Vol. 5, Page 3004-3004, Year 2014
Publish dateOct 8, 2013 (structure data deposition date)
AuthorsSmietanski, M. / Werner, M. / Purta, E. / Kaminska, K.H. / Stepinski, J. / Darzynkiewicz, E. / Nowotny, M. / Bujnicki, J.M.
External linksNat Commun / PubMed:24402442
MethodsX-ray diffraction
Resolution1.9 - 2.704 Å
Structure data

PDB-4n48:
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with capped RNA fragment
Method: X-RAY DIFFRACTION / Resolution: 2.704 Å

PDB-4n49:
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with m7GpppG and SAM
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4n4a:
Cystal structure of Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-MGT:
7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/RNA / methyltransferase / mRNA cap methylation / capped mRNA / TRANSFERASE-RNA complex / TRANSFERASE / mRNA

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