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Structure paper

TitleCrystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Journal, issue, pagesFebs Lett., Vol. 587, Page 3859-3868, Year 2013
Publish dateApr 27, 2011 (structure data deposition date)
AuthorsWu, H. / Siarheyeva, A. / Zeng, H. / Lam, R. / Dong, A. / Wu, X.H. / Li, Y. / Schapira, M. / Vedadi, M. / Min, J.
External linksPubMed:24396869
MethodsX-ray diffraction
Resolution1.8 - 1.85 Å
Structure data

PDB-3rq4:
Crystal structure of suppressor of variegation 4-20 homolog 2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3s8p:
Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SUV420H2 / suppressor / variegation 4-20 homolog 2 / Structural Genomics / Structural Genomics Consortium / SGC / SET domain / histone methyltransferase / transcription regulation / histone lysine / SAM / methylation / nucleus / chromosome

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