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Structure paper

TitleStructural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 2331-2343, Year 2014
Publish dateOct 23, 2013 (structure data deposition date)
AuthorsMurase, T. / Eugenio, L. / Schorr, M. / Hussack, G. / Tanha, J. / Kitova, E.N. / Klassen, J.S. / Ng, K.K.
External linksJ. Biol. Chem. / PubMed:24311789
MethodsX-ray diffraction
Resolution1.75 - 2.61 Å
Structure data

PDB-4nbx:
Crystal Structure of Clostridium difficile Toxin A fragment TcdA-A1 Bound to A20.1 VHH
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-4nby:
Crystal Structure of TcdA-A2 Bound to Two Molecules of A20.1 VHH
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-4nbz:
Crystal Structure of TcdA-A1 Bound to A26.8 VHH
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-4nc0:
Crystal Structure of TcdA-A2 Bound to A26.8 VHH
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4nc1:
Crystal Structure of TcdA-A2 Bound to A20.1 VHH and A26.8 VHH
Method: X-RAY DIFFRACTION / Resolution: 2.61 Å

PDB-4nc2:
Crystal structure of TcdB-B1 bound to B39 VHH
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • clostridium difficile (bacteria)
  • lama glama (llama)
KeywordsIMMUNE SYSTEM / Antibody-antigen complex

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