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Structure paper

TitleConversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 53, Page 824-828, Year 2014
Publish dateOct 29, 2013 (structure data deposition date)
AuthorsHotta, K. / Keegan, R.M. / Ranganathan, S. / Fang, M. / Bibby, J. / Winn, M.D. / Sato, M. / Lian, M. / Watanabe, K. / Rigden, D.J. / Kim, C.Y.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:24302672
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-4nec:
Conversion of a Disulfide Bond into a Thioacetal Group during Echinomycin Biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-NA:
Unknown entry

ChemComp-QUI:
2-CARBOXYQUINOXALINE

ChemComp-ACT:
ACETATE ION

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

ChemComp-HOH:
WATER

Source
  • streptomyces lasaliensis (bacteria)
  • streptomyces echinatus (bacteria)
KeywordsTRANSFERASE/ANTIBIOTIC / Methyltransferase / SAM-dependent methyltransferase / TRANSFERASE-ANTIBIOTIC complex

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