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Structure paper

TitleRNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Journal, issue, pagesNucleic Acids Res., Vol. 42, Page 2758-2773, Year 2014
Publish dateOct 2, 2012 (structure data deposition date)
AuthorsSurana, P. / Satchidanandam, V. / Nair, D.T.
External linksNucleic Acids Res. / PubMed:24293643
MethodsX-ray diffraction
Resolution2.28 - 3.65 Å
Structure data

PDB-4hdg:
Crystal Structure of viral RdRp in complex with GTP
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-4hdh:
Crystal Structure of viral RdRp in complex with ATP
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

PDB-4mtp:
RdRp from Japanesese Encephalitis Virus
Method: X-RAY DIFFRACTION / Resolution: 3.65 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • japanese encephalitis virus
KeywordsTRANSFERASE / DNA/RNA polymerases / RNA dependent RNA polymerase / GTP / RNA directed RNA polymerase / Nucleotidyltransferases / apo

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