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Structure paper

TitleCrystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Journal, issue, pagesImmunity, Vol. 39, Page 1032-1042, Year 2013
Publish dateSep 10, 2013 (structure data deposition date)
AuthorsLuoma, A.M. / Castro, C.D. / Mayassi, T. / Bembinster, L.A. / Bai, L. / Picard, D. / Anderson, B. / Scharf, L. / Kung, J.E. / Sibener, L.V. ...Luoma, A.M. / Castro, C.D. / Mayassi, T. / Bembinster, L.A. / Bai, L. / Picard, D. / Anderson, B. / Scharf, L. / Kung, J.E. / Sibener, L.V. / Savage, P.B. / Jabri, B. / Bendelac, A. / Adams, E.J.
External linksImmunity / PubMed:24239091
MethodsX-ray diffraction
Resolution2.6032 - 3.3 Å
Structure data

PDB-4mng:
Structure of the DP10.7 TCR with CD1d-sulfatide
Method: X-RAY DIFFRACTION / Resolution: 3.0058 Å

PDB-4mnh:
Structure of the DP10.7 TCR
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-4mq7:
Structure of human CD1d-sulfatide
Method: X-RAY DIFFRACTION / Resolution: 2.6032 Å

PDB-4ndm:
Structure of the AB18.1 TCR
Method: X-RAY DIFFRACTION / Resolution: 3.0065 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CIS:
(15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunglobulin / Histocompatibility Antigens / CD1 / Immunological / lymphocytes / gamma delta T cell / T cell recognition / self-recognition / myelin / intestinal epithelial lymphocytes / Human / Lipid binding / self-ligand / Glycoproteins / Cell-surface receptors / Immunoglobulin / T cell receptor / activation / intraepithelial lymphocytes / CD1d / glycolipids / non-classical MHC / gamma-delta / Humans / T cells / non-classical / lipids / restriction / major histocompatibility complex / antigen presentation / self-ligands

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