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-Structure paper
Title | beta-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of an Unprecedented Stabilized Acyl-Enzyme. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 135, Page 18358-18369, Year 2013 |
Publish date | Mar 19, 2013 (structure data deposition date) |
Authors | Rodkey, E.A. / McLeod, D.C. / Bethel, C.R. / Smith, K.M. / Xu, Y. / Chai, W. / Che, T. / Carey, P.R. / Bonomo, R.A. / van den Akker, F. / Buynak, J.D. |
External links | J. Am. Chem. Soc. / PubMed:24219313 |
Methods | X-ray diffraction |
Resolution | 1.14 Å |
Structure data | PDB-4jpm: |
Chemicals | ChemComp-MA4: ChemComp-1OG: ChemComp-EPE: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / CLASS A BETA-LACTAMASE / HYDROLASE-HYDROLASE INHIBITOR complex |