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Structure paper

TitleAltered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 36624-36635, Year 2013
Publish dateMay 7, 2013 (structure data deposition date)
AuthorsTang, W.K. / Xia, D.
External linksJ. Biol. Chem. / PubMed:24196964
MethodsX-ray diffraction
Resolution1.98 - 2.96 Å
Structure data

PDB-4kln:
Structure of p97 N-D1 A232E mutant in complex with ATPgS
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

PDB-4ko8:
Structure of p97 N-D1 R155H mutant in complex with ATPgS
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

PDB-4kod:
Structure of p97 N-D1 R155H mutant in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Transport protein / ATPase / AAA ATPase

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