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TitleCrystal structure of a soluble cleaved HIV-1 envelope trimer.
Journal, issue, pagesScience, Vol. 342, Page 1477-1483, Year 2013
Publish dateOct 24, 2013 (structure data deposition date)
AuthorsJulien, J.P. / Cupo, A. / Sok, D. / Stanfield, R.L. / Lyumkis, D. / Deller, M.C. / Klasse, P.J. / Burton, D.R. / Sanders, R.W. / Moore, J.P. ...Julien, J.P. / Cupo, A. / Sok, D. / Stanfield, R.L. / Lyumkis, D. / Deller, M.C. / Klasse, P.J. / Burton, D.R. / Sanders, R.W. / Moore, J.P. / Ward, A.B. / Wilson, I.A.
External linksScience / PubMed:24179159
MethodsX-ray diffraction
Resolution4.7 Å
Structure data

PDB-4nco:
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
Method: X-RAY DIFFRACTION / Resolution: 4.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • human immunodeficiency virus 1
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Type-1 membrane fusion glycoprotein trimer / HIV-1 envelope / gp120 / gp41 / membrane fusion / viral entry / CD4 / CCR5/CXCR4 / broadly neutralizing antibodies / viral surface / VIRAL PROTEIN-IMMUNE SYSTEM complex

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