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Structure paper

TitleA Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.
Journal, issue, pagesPlos Pathog., Vol. 9, Page 3640-, Year 2013
Publish dateNov 2, 2012 (structure data deposition date)
AuthorsHellert, J. / Weidner-Glunde, M. / Krausze, J. / Richter, U. / Adler, H. / Fedorov, R. / Pietrek, M. / Ruckert, J. / Ritter, C. / Schulz, T.F. / Luhrs, T.
External linksPlos Pathog. / PubMed:24146614
MethodsX-ray diffraction
Resolution2.3 - 3.911 Å
Structure data

PDB-2ypy:
KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.453 Å

PDB-2ypz:
KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.199 Å

PDB-2yq0:
KSHV LANA (ORF73) C-terminal domain, octameric ring: cubic crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.911 Å

PDB-2yq1:
MHV-68 LANA (ORF73) C-terminal domain: triclinic crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • human herpesvirus 8 type m
  • murid herpesvirus 4 (Murine herpesvirus 68)
KeywordsVIRAL PROTEIN / VIRAL PROTEIN N / LATENCY-ASSOCIATED NUCLEAR ANTIGEN / LANA-1 / DNA-BINDING DOMAIN / ORIGIN-BINDING DOMAIN / OLIGOMERIZATION DOMAIN / KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS / GAMMAHERPESVIRUS / RHADINOVIRUS / PRIMARY EFFUSION LYMPHOMA / MULTICENTRIC CASTLEMAN'S DISEASE / TUMOR VIRUS / CANCER / MURID HERPESVIRUS 4 / MUHV-4 / MURID HERPESVIRUS 68 / MHV-68 / LATENCY- ASSOCIATED NUCLEAR ANTIGEN / MLANA / KSHV

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