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Structure paper

TitleStructural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.
Journal, issue, pagesCell Res., Vol. 24, Page 190-203, Year 2014
Publish dateJun 19, 2013 (structure data deposition date)
AuthorsGuo, F. / Stanevich, V. / Wlodarchak, N. / Sengupta, R. / Jiang, L. / Satyshur, K.A. / Xing, Y.
External linksCell Res. / PubMed:24100351
MethodsX-ray diffraction
Resolution2.82 Å
Structure data

PDB-4lac:
Crystal Structure of Protein Phosphatase 2A (PP2A) and PP2A phosphatase activator (PTPA) complex with ATPgammaS
Method: X-RAY DIFFRACTION / Resolution: 2.82 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-MN:
Unknown entry

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHydrolase/signaling protein / PP2A / PTPA / protein phosphatase / signaling pathway regulation / chaperone / Hydrolase-signaling protein complex

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