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TitleStructural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Journal, issue, pagesStructure, Vol. 21, Page 1-13, Year 2013
Publish dateOct 28, 2012 (structure data deposition date)
AuthorsJost, C. / Schilling, J. / Tamaskovic, R. / Schwill, M. / Honegger, A. / Plueckthun, A.
External linksStructure / PubMed:24095059
MethodsX-ray diffraction
Resolution2.55 - 3.2 Å
Structure data

PDB-4hrl:
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-4hrm:
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-4hrn:
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic (others)
KeywordsTRANSFERASE/DE NOVO PROTEIN / TRANSFERASE-DE NOVO PROTEIN complex

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