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Structure paper

TitleSelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep).
Journal, issue, pagesPlos One, Vol. 8, Page e71512-e71512, Year 2013
Publish dateMar 27, 2013 (structure data deposition date)
AuthorsGuellouz, A. / Valerio-Lepiniec, M. / Urvoas, A. / Chevrel, A. / Graille, M. / Fourati-Kammoun, Z. / Desmadril, M. / van Tilbeurgh, H. / Minard, P.
External linksPlos One / PubMed:24014183
MethodsX-ray diffraction
Resolution1.9 - 2.6 Å
Structure data

PDB-4jw2:
Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4jw3:
Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep)
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
  • streptomyces malayensis (bacteria)
KeywordsDE NOVO PROTEIN/protein binding / alpha-helical proteins / Proteins engineered to bind to various partners / DE NOVO PROTEIN-protein binding complex / DNA binding protein/de novo protein / alpha-helical protein / Protein engineered to interact with protein of interest / NCS 3tes24 variant / DNA binding protein-de novo protein complex

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